Healthcare
BiomimTech: Next-generation Drug Development

Brief

Drug discovery redefined

Technology Overview

An Organ-on-a-Chip device that recreates the micro-environment of the lymph node, which is the meeting point for immune cells in the human body. The chip is coupled with a computational platform that uses artificial intelligence to analyze immune cell behavior. The ultimate goal of the technology is to assess the effect of candidate drugs on the immune system in an in-vitro, physiologically-relevant environment that eliminates the need for animal testing and guarantees better performance during clinical trials.


Inventors
  • Cesare Stefanini
  • Jeremy Teo
  • Aya Shanti
  • Amal Abdullah
  • Bisan Samara
Competitive Advantage
  • Transparent chip that allows clear imaging of cells in-vitro
  • Microfluidics that allows for efficient use of reagents
  • Biocompatible and sterile to maintain cell viability
  • User-friendly and enables easy setup of experiments
  • Easily reproducible, allowing for batch production
Market Application
  • In-vitro validation of immune compatibility for new drugs under development
  • Growing market of more than 5.7 billion USD
  • Novel proprietary technology for quick drug discovery by mimicking in-vivo environment
  • Applicable to other markets such as personalized medicine and diagnostics
Intellectual Property

US 2020-0276586 A1

Contact

ip@ku.ac.ae

SweeTest: An Evolved Low-Cost Sensor for Sugar Monitoring

Brief

Make your life sweet enough

Technology Overview

This is a low-cost glucose sensor that can be used to monitor sugar levels in human fluid (saliva, sweat, blood). It does not require a special solution to dilute the fluid before applying it to the sensor which results in a more compact, lower cost and long shelf life device. The sensor can measure glucose concentration levels between 40-180 mg/dl, which covers the necessary monitoring range in human blood.


Inventors
  • Heba Abunahla
  • Baker Mohammad
  • Anas Alazzam
  • Maguy Abi Jaoude
  • Mahmoud Al-Qutayri
Competitive Advantage
  • Low- cost
  • Low-power
  • Potential flexible product
  • Non-invasive potential use with body fluids like saliva or sweat
  • Long shelf life
Market Application
  • Household glucose monitoring
  • Can be sold in pharmacies
  • Can be used in hospitals
Intellectual Property

WO 2019/234596 A1

Contact

ip@ku.ac.ae

Medical Device for Detecting a Ventricular Arrhythmia Event

Brief

Protection against sudden death from ventricular arrhythmias

Technology Overview

The medical device for detecting a ventricular arrhythmia is comprised of input circuitry configured to receive an electrocardiogram signal, processing circuitry coupled to the input circuitry, and feature extraction circuitry coupled to the processing circuitry. In addition, machine learning circuitry is coupled to the feature extraction circuitry that includes a decision block to alarm the user if a ventricular arrhythmia is detected.


Inventors
  • Ahsan Habib Khandoker
  • Baker Mohammad
  • Hani Saleh
  • Mahmoud Al Qutayri
  • Mohammed Elnaggar
  • Nourhan Bayasi
  • Temesghen Habte
Competitive Advantage
  • Provides a high-performance yet efficient method for early detection of the onset of ventricular arrhythmia
  • Detects abnormal electrocardiogram intervals
  • Discriminates ventricular arrhythmias versus non-ventricular arrhythmias resulting in high sensitivity
Market Application
  • Medical device
  • Cardiovascular disease
  • Cardiac arrhythmias
Intellectual Property

U.S. 9,717,438

Contact

ip@ku.ac.ae

Machine-Based Patient-Specific Seizure Classification System

Brief 

Reducing the impact of seizures in epilepsy patients

Technology Overview

The occurrence of random and sudden seizures in epilepsy patients can be stressful and potentially dangerous. The machine-based patient-specific seizure classification system could detect seizure precursors and potentially suppress the seizures. The system-on-chip (SoC) includes a hardware-efficient log-linear engine to realize non-linear support vector machine-based seizure detection. Also, the system enables multi-channel electroencephalography data acquisition and storage.


Inventors
  • Jerald Yoo
  • Muhammad Altaf
Competitive Advantage
  • Enables detection of seizure precursors with potential treatment to suppress the seizures
  • Achieves high accuracy (>95%) with low false alarms
  • Minimizes seizure detection delay
  • Could improve treatment outcome in epilepsy patients
Market Application
  • Medical devices
  • Electronics
  • Patient monitoring and treatment
  • System-on chip for detecting and treating a medical condition
  • Epilepsy
Intellectual Property

U.S. 9,848,793

Contact

ip@ku.ac.ae

Cellulosic Gel Material as a Pharmaceutical Excipient

Brief

Improved process of preparing pharmaceutical tablets

Technology Overview

A gel material from structure-modified or processed cellulose combined with an active pharmaceutical ingredient can be used to improve the process of tablet production. The approach introduces a continuous process that can reduce labor, time, and cost of production. In addition, the approach results in an improved tablet with desirable properties.


Inventors
  • Raed Hashaikeh
  • Hatem Abushammala
Competitive Advantage
  • Results in a high yield, continuous, and efficient production process that can be implemented at a commercial scale
  • Eliminates the need of using a tablet compression machine to produce a hard tablet
  • Produces a tablet with beneficial attributes including hardness and drug delivery
Market Application

Production of pharmaceutical products in tablet form

Intellectual Property

U.S. 9,446,000

Contact

ip@ku.ac.ae