Cardiovascular disease (CVD) is the major cause of death in the UAE and Korea, causing one in every five deaths. Some lifestyle factors (such as an unhealthy diet, lack of exercise, and smoking), known to contribute to a higher risk of CVD, are also common in people with mental health issues (such as depression). Integrated Cardiac and Mental Rehabilitation can significantly improve mortality and morbidity rates, leading to longer independent living and a reduced use of healthcare resources. The proposed collaborative project, named Mind My Heart, sets as an overall goal to introduce a personalized home-based rehabilitation program, enabling lifestyle behavioral change towards increased quality of life with personalized management for CVD and mental health issues. The overall concept of the Mind My Heart platform is easily transferable to address other diseases providing market opportunities for the commercialization.