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Integrated Approach to Study Gestational Diabetes Mellitus in Emirati Women Using Clinical, Epidemiological, Metabolomic, and Genomic Data

Principal Investigator
Wael Osman
Department
Chemistry
Focus Area
Healthcare
Integrated Approach to Study Gestational Diabetes Mellitus in Emirati Women Using Clinical, Epidemiological, Metabolomic, and Genomic Data

Gestational diabetes mellitus (GDM) is a major health problem as it carries devastating effects for women during their reproductive age as well as their babies. The exact mechanisms underlying this condition remain unknown. Currently, there are no diagnostic markers for GDM in early pregnancy; although early diagnosis was found to correlate with better outcomes from the disease. With the increasing prevalence of GDM all over the word, including the UAE, certain questions arise such as:

    • Who is at risk of GDM?
    • What are the gene(s) involved in predisposition to this condition?
    • What effect(s) does environmental factors have on the disease susceptibility?
    • What effect(s) the gene-environment interactions play on susceptibility of GDM?
    • What are the possible biomarkers for early diagnosis?
Integrated Approach to Study Gestational Diabetes Mellitus in Emirati Women Using Clinical, Epidemiological, Metabolomic, and Genomic Data