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- Advanced Digital & Additive Manufacturing Center
- Advanced Power and Energy Center
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- Center for Biotechnology
- Center for Catalysis and Separation
- Center for Cyber-Physical Systems
- Center for Membranes and Advanced Water Technology
- Emirates ICT Innovation Center (EBTIC)
- Emirates Nuclear Technology Center
- Healthcare Engineering Innovation Center
- KU Center for Autonomous Robotic Systems
- Khalifa University Space Technology and Innovation Center
- Research Center for Digital Supply Chain and Operations Management
- Research and Innovation Center on CO2 and Hydrogen
- Space and Planetary Science Center
- Sustainable Bioenergy Research Consortium
- System-on-Chip Lab
